Oxygen chambers may ease opioid withdrawal, small study suggests

This early-phase study tested whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) could reduce withdrawal symptoms in 25 adults with opioid use disorder who were gradually reducing their methadone dose. Participants received either real HBOT at two different pressures or a sham treatment. The goal was to see if HBOT made withdrawal less uncomfortable and helped people stick with their dose reductions.