Hydroxychloroquine's effect on arteries in APS studied, but trial cut short
NCT ID NCT02595346
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether hydroxychloroquine (Plaquenil) could improve artery function in people with antiphospholipid syndrome (APS), a condition that raises the risk of blood clots. Researchers planned to give either hydroxychloroquine or a placebo to 25 participants and measure changes in blood vessel dilation. However, the trial was terminated early, so the results are limited and not conclusive.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hydroxychloroquine (also known as Plaquenil)
What this could lead to
If it worked, this could point toward a way to improve blood vessel health and reduce clotting risk in people with antiphospholipid syndrome.
What could go wrong
The trial was terminated early and very small (25 people), so results are limited. Hydroxychloroquine can cause side effects like vision problems or heart issues in some people.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Rouen University Hospital
Rouen, 76031, France