Heart safety check for experimental liver drug

NCT ID NCT07263152

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This early-stage trial tested whether a single dose of hydronidone, an experimental drug for liver fibrosis, changes the heart's electrical activity (QTc interval) in 48 healthy Chinese adults. Participants received one of three doses or a placebo, and researchers measured how the drug affected their heart rhythm over time. The goal was to check safety, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Hydronidone capsules
What this could lead to
If successful, this study could help determine a safe dose range for hydronidone in future trials for liver fibrosis.
What could go wrong
This is an early-phase safety study in healthy people, not patients. It only looks at heart rhythm effects, not whether the drug works for liver disease.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Gobroad Hospital

    Beijing, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.