Injectable hydrogel could ease back pain without surgery
NCT ID NCT06011551
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a hydrogel implant injected into damaged spinal discs to treat degenerative disc disease. About 225 adults with chronic low back pain will receive either the implant or standard care like physical therapy. The goal is to see if the implant safely improves pain and function over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hydrogel implant (injected into the disc)
What this could lead to
If it works, this could offer a less invasive way to treat chronic back pain from disc degeneration, potentially delaying or avoiding surgery.
What could go wrong
This is a pivotal study, but the implant is new and long-term results are unknown. There is a risk of infection, implant failure, or no improvement over standard care.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Locations
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Alabama Clinical Therapeutics
RECRUITINGBirmingham, Alabama, 35235, United States
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Beam Research (Beam Radiology)
RECRUITINGCalgary, Alberta, T3R 0N2, Canada
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Boomerang Healthcare (IPM Medical Group)
RECRUITINGWalnut Creek, California, 94598, United States
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Clinical Investigations
RECRUITINGEdmond, Oklahoma, 73103, United States
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DBPS Research (The Denver Spine & Pain Institute)
RECRUITINGGreenwood Village, Colorado, 80111, United States
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Horizon Clinical Research (Southern Pain and Spine)
RECRUITINGJasper, Georgia, 30143, United States
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NRSA Group (Florida Spine & Pain Specialists)
RECRUITINGRiverview, Florida, 33569, United States
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Neuroscience Research Center, LLC
RECRUITINGOverland Park, Kansas, 66210, United States
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Precision Spine Care
RECRUITINGTyler, Texas, 75701, United States
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Source Healthcare
RECRUITINGSanta Monica, California, 90403, United States
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Southwest Florida Pain Center
RECRUITINGPort Charlotte, Florida, 33948, United States
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Spine Institute of Louisiana (The Spine Network)
RECRUITINGShreveport, Louisiana, 71101, United States
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The Orthopaedic Institute
RECRUITINGGainesville, Florida, 32607, United States
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Virginia iSpine Physicians
RECRUITINGRichmond, Virginia, 23238, United States
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