Injectable hydrogel could ease back pain without surgery

NCT ID NCT06011551

Recruiting now Disease control Sponsor: ReGelTec, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study tests a hydrogel implant injected into damaged spinal discs to treat degenerative disc disease. About 225 adults with chronic low back pain will receive either the implant or standard care like physical therapy. The goal is to see if the implant safely improves pain and function over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hydrogel implant (injected into the disc)
What this could lead to: If it works, this could offer a less invasive way to treat chronic back pain from disc degeneration, potentially delaying or avoiding surgery.
What could go wrong: This is a pivotal study, but the implant is new and long-term results are unknown. There is a risk of infection, implant failure, or no improvement over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEGENERATIVE DISC DISEASE (DDD)

Contacts and locations

Locations

Alabama Clinical Therapeutics
RECRUITING

Birmingham, Alabama, 35235, United States
Beam Research (Beam Radiology)
RECRUITING

Calgary, Alberta, T3R 0N2, Canada
Boomerang Healthcare (IPM Medical Group)
RECRUITING

Walnut Creek, California, 94598, United States
Clinical Investigations
RECRUITING

Edmond, Oklahoma, 73103, United States
DBPS Research (The Denver Spine & Pain Institute)
RECRUITING

Greenwood Village, Colorado, 80111, United States
Horizon Clinical Research (Southern Pain and Spine)
RECRUITING

Jasper, Georgia, 30143, United States
NRSA Group (Florida Spine & Pain Specialists)
RECRUITING

Riverview, Florida, 33569, United States
Neuroscience Research Center, LLC
RECRUITING

Overland Park, Kansas, 66210, United States
Precision Spine Care
RECRUITING

Tyler, Texas, 75701, United States
Source Healthcare
RECRUITING

Santa Monica, California, 90403, United States
Southwest Florida Pain Center
RECRUITING

Port Charlotte, Florida, 33948, United States
Spine Institute of Louisiana (The Spine Network)
RECRUITING

Shreveport, Louisiana, 71101, United States
Tenet Florida Physician Services II (Cantor Spine Center at The Paley Orthopedic and Spine Institute)
RECRUITING

West Palm Beach, Florida, 33407, United States
The Orthopaedic Institute
RECRUITING

Gainesville, Florida, 32607, United States
Virginia iSpine Physicians
RECRUITING

Richmond, Virginia, 23238, United States

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