Brain training with EEG and MRI shows promise for depression
NCT ID NCT04450186
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tested a new type of brain training called neurofeedback for people with depression. Participants learned to control their own brain activity using real-time feedback from both EEG and fMRI scans. The goal was to see if combining these two methods could help improve lingering cognitive problems after a depressive episode. The study involved 31 adults and was designed to prepare for a larger trial.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
EEG/fMRI neurofeedback
What this could lead to
If successful, this could point toward a new non-drug therapy for depression that helps patients train their own brain activity to reduce symptoms.
What could go wrong
This is a very small pilot study (31 people) testing feasibility, not effectiveness. Results may not apply to all depressed patients, and the technique is still experimental.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU
Rennes, France