Engineered immune cells take on tough blood cancers

NCT ID NCT04684563

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 22 times

Summary

This early-phase trial tests a new treatment called huCART19-IL18 for people with certain blood cancers (leukemia and lymphoma) that have come back or not responded to standard therapy. The treatment uses a patient's own immune cells, modified to better find and attack cancer cells. The main goals are to check safety, find the best dose, and see if the cells can be made reliably for each patient.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.