Immune booster shot aims to speed recovery after cord blood transplant

NCT ID NCT04707300

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests whether injecting special immune progenitor cells (HTLPs) can help the immune system recover faster after a cord blood transplant in adults with blood cancers. Ten participants will receive the injection alongside their transplant. The goal is to see if it is safe and if it speeds up T-cell recovery, which could lower infection risk and improve outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Human T Lymphoid Progenitor (HTLP) cells

What this could lead to

If successful, this could lead to faster immune recovery after cord blood transplants, reducing infection risk and improving outcomes for blood cancer patients.

What could go wrong

This is a very small, early-phase trial (only 10 participants) testing safety and feasibility. The approach may not work or could cause severe graft-versus-host disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEMATOLOGIC MALIGNANCY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute myeloid leukemia hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm Neoplasm, Residual

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hematology department / Necker Children's Hospital

    RECRUITING

    Paris, Île-de-France Region, 75015, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Saint Louis

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IUCT Oncopole Toulouse

    RECRUITING

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Gustave Roussy

    NOT_YET_RECRUITING

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Service d'Hématologie et thérapie cellulaire / CHU of Bordeaux

    RECRUITING

    Pessac, 33604, France

    Contact Email: •••••@•••••