Breathing technique may tune the nervous system to improve blood sugar

NCT ID NCT06739993

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests whether a specific breathing exercise, called resonant frequency breathing with heart rate variability biofeedback, can improve how the body handles sugar in people with prediabetes. The training aims to calm the body's stress response by increasing heart rate variability, which may positively influence glucose metabolism. Sixty adults with prediabetes will be randomly assigned to either this breathing training or an anti-stress program, and their glucose metabolism will be measured using an oral glucose tolerance test.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Resonance frequency breathing with heart rate variability biofeedback training
What this could lead to
If effective, this drug-free breathing technique could offer a new way to help people with prediabetes improve blood sugar control and potentially lower their risk of developing type 2 diabetes.
What could go wrong
This is an early-stage trial with a modest number of participants, so results may not be conclusive or widely applicable. The training requires regular practice, and its effect on glucose metabolism is not yet proven.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Medical Center Mainz - Medical Psychology and Medical Sociology

    RECRUITING

    Mainz, Mainz, 55128, Germany

  • University Medical Center of the Johannes-Gutenberg University, Department of Medical Psychology and Medical Sociology

    NOT_YET_RECRUITING

    Mainz, Rhineland-Palatinate, 55128, Germany

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