New shot aims to silence hepatitis b virus for good

NCT ID NCT06425341

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called HRS-5635, given alone or with other medications, in people with chronic hepatitis B. The goal is to lower or clear the hepatitis B surface antigen (HBsAg) from the blood, which could mean better long-term control of the virus. About 369 adults who are already on standard antiviral therapy will take part. The study is in Phase 2, meaning it is still early and focused on finding the right dose and checking safety.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nanfang Hospital

    RECRUITING

    Guangzhou, Guangdong, 510515, China

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Other studies related to the condition(s) this trial covers.