New shot aims to silence hepatitis b virus in patients on long-term pills

NCT ID NCT06425341

First seen Nov 17, 2025 · Last updated May 15, 2026 · Updated 13 times

Summary

This study tests an experimental injection called HRS-5635, given alone or with other drugs, in 369 adults with chronic hepatitis B. Participants must already be on standard antiviral pills with undetectable virus levels. The main goal is to see if the treatment can lower or clear hepatitis B surface antigen from the blood, which would mean better disease control. This is a Phase 2 trial, so it is still early and focuses on safety and how well the drug works.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nanfang Hospital

    RECRUITING

    Guangzhou, Guangdong, 510515, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.