Could 2 HPV vaccine doses be enough? new study says maybe.
NCT ID NCT03943875
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether 2 doses of the HPV vaccine (Gardasil 9) protect as well as the standard 3 doses in people aged 15 to 26. Researchers measured antibody levels against nine HPV types. The goal is to see if a simpler schedule could work, making vaccination easier and cheaper.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
9-valent HPV vaccine (Gardasil 9)
What this could lead to
If 2 doses work as well as 3, it could simplify HPV vaccination schedules, reduce costs, and make it easier for more people to get protected against HPV-related cancers.
What could go wrong
This is a completed Phase 4 study, but it only measured short-term antibody responses, not long-term cancer prevention. Two doses may not provide the same lasting protection as three doses.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Texas Medical Branch
Galveston, Texas, 77555, United States