New vaccine may help throat cancer patients avoid radiation

NCT ID NCT06223568

First seen Sep 30, 2025 · Last updated May 14, 2026 · Updated 29 times

Summary

This study tests whether adding an experimental vaccine (PRGN-2009) to standard chemotherapy can improve outcomes for people with newly diagnosed HPV-related throat cancer. About 70 adults will receive either chemo alone or chemo plus the vaccine, followed by surgery. The goal is to see if the combination can eliminate the need for radiation, which often causes serious side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

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