New DNA vaccine aims to clear Cancer-Causing HPV

NCT ID NCT06210854

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This phase 2 trial tests a DNA vaccine called pBI-11 in 48 women with persistent HPV16 or HPV18 cervical infection. The vaccine is designed to boost the immune system to clear the virus. Participants receive the vaccine or a placebo via injection with a special device. The study focuses on safety and whether the virus disappears.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pBI-11 DNA vaccine

What this could lead to

If successful, this vaccine could help clear persistent HPV16/18 infections, reducing the risk of cervical cancer.

What could go wrong

This is an early phase 2 trial with only 48 participants, so results may not apply widely. The vaccine may not clear the virus or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

human papilloma virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Email: •••••@•••••

    Contact

  • University of Alabama at Birmingham

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35249, United States

    Contact Email: •••••@•••••

    Contact