Simple blood test could help monitor aggressive brain tumors

NCT ID NCT05157594

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether a blood test measuring a protein called hPG80 (progastrin) can help track high-grade brain tumors like glioblastoma. Researchers took blood samples from 30 patients before, during, and after radiation and chemotherapy. The goal was to see if hPG80 levels change with tumor progression or treatment, potentially offering a less invasive way to monitor the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test to monitor brain tumor progression and response to treatment.

What could go wrong

This is a very small pilot study (30 people) with no control group, so results may not apply broadly. The test is experimental and not yet proven to be reliable.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anaplastic astrocytoma anaplastic oligodendroglioma glioblastoma glioma malignant glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Jean PERRIN

    Clermont-Ferrand, 63011, France