Scientists probe Brain's role in Ketamine's Fast-Acting depression relief
NCT ID NCT03973268
Summary
This study aims to understand how ketamine, a drug known to relieve depression symptoms within hours, works in the brain. Researchers will test whether blocking a specific brain receptor (called AMPA) reduces ketamine's antidepressant effects. About 70 adults with major depression that hasn't improved with standard treatments will stay at a research center for 5 weeks to undergo brain scans, tests, and receive ketamine infusions with either a test drug or a placebo.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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