New device aims to keep donor hearts healthier for transplant

NCT ID NCT07556588

Recruiting now Disease control Sponsor: XVIVO Perfusion Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early trial tests a device that keeps donor hearts cool and oxygenated during transport, instead of the usual ice cooler. The goal is to see if this method is safe and works for heart transplants from both brain-dead and circulatory-death donors. Twenty adult patients awaiting a heart transplant will take part. If it works, it could lead to better heart preservation and more successful transplants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: XVIVO Heart Assist Transport System (device for hypothermic oxygenated perfusion of donor hearts)
What this could lead to: If successful, this device could help more donor hearts be safely transported and transplanted, potentially increasing the number of heart transplants available.
What could go wrong: This is a very early, small trial with only 20 patients. The device may not improve outcomes or could have unforeseen complications. Results may not apply to all transplant centers.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

UZ Leuven
RECRUITING

Leuven, B-3000, Belgium

Contact Phone: •••-•••-•••• Email: •••••@•••••

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