Could a Head-Zapping device at home beat chronic fatigue?

NCT ID NCT05791812

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a gentle electrical brain stimulation device, used at home under remote supervision, can help reduce fatigue in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Twenty participants will use the device for 20 minutes each weekday over six weeks. The main goals are to see if the treatment is practical and if it improves fatigue and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial direct current stimulation (tDCS) device

What this could lead to

If it works, this could offer a convenient home-based treatment to reduce fatigue and improve quality of life for people with ME/CFS.

What could go wrong

This is a very small early study with only 20 participants and no placebo group, so results may not be reliable or generalizable. The treatment may also cause discomfort or skin irritation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

myalgic encephalomeyelitis/chronic fatigue syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Psychiatry and Psychotherapy, University of Regensburg

    Regensburg, 93055, Germany