Could a High-Fat diet reset energy in long COVID?
NCT ID NCT07745699
First seen Aug 04, 2026 · Last updated Aug 07, 2026 · Updated 3 times
Summary
This trial tests whether a 12-week ketogenic diet program, delivered entirely online, is practical and acceptable for adults with Long COVID who also have ME/CFS and dysautonomia. Participants follow a low-carb, high-fat diet with vitamin B1 and electrolyte support, plus weekly virtual nutrition coaching. The study tracks adherence, safety, and satisfaction, and also measures changes in fatigue, sleep, mood, and daily functioning. The goal is to see if this remote approach could be a viable way to ease symptoms and improve quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ketogenic metabolic therapy (a low-carb, high-fat diet with vitamin B1 and electrolyte support, delivered via telehealth)
- What this could lead to
- If successful, this could point toward a practical, home-based dietary approach to ease fatigue and autonomic symptoms in Long COVID, potentially improving daily functioning and quality of life.
- What could go wrong
- This is a small feasibility study with only 11 participants, so results may not apply broadly. The diet is restrictive and may be hard to follow, and benefits are not guaranteed.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National University of Natural Medicine
Portland, Oregon, 97229, United States
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