At-Home brain zaps show promise for depression relief

NCT ID NCT07228468

Recruiting now Symptom relief Sponsor: King's College London Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a safe, non-invasive brain stimulation treatment called tDCS that people can use at home to ease depression. About 438 adults with major depression will either receive active tDCS plus their usual care, or just usual care alone. The goal is to see if adding tDCS reduces depressive symptoms more than standard treatment alone.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER (MDD)

Contacts and locations

Locations

Cardiff and Vale Health Board
NOT_YET_RECRUITING

Cardiff, CF24 4HQ, United Kingdom
Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust
NOT_YET_RECRUITING

Newcastle, NE4 5PL, United Kingdom
Hampshire and Isle of Wight Healthcare NHS Foundation Trust
NOT_YET_RECRUITING

Southampton, SO14 3DT, United Kingdom
Northamptonshire Healthcare NHS Foundation Trust
NOT_YET_RECRUITING

Northampton, NN5 6UD, United Kingdom
Nottinghamshire Healthcare NHS Foundation Trust
NOT_YET_RECRUITING

Nottingham, NG7 2UH, United Kingdom
South London and Maudsley NHS Foundation Trust
RECRUITING

London, SE5 8AF, United Kingdom

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