New hope for tough head and neck cancers: targeted drug trial opens

NCT ID NCT06857279

Recruiting now Disease control Sponsor: Shanghai Henlius Biotech Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called HLX43 in people whose head and neck cancer has returned or spread to other parts of the body. The drug works by targeting a protein (PD-L1) on cancer cells to help the immune system attack them. About 167 adults aged 18 to 75 will take part to see if the drug shrinks tumors and to check for side effects.

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Conditions

The condition(s) this trial relates to.

head and neck carcinoma head and neck squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARCINOMA OF HEAD AND/OR NECK

Contacts and locations

Locations

Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, 200032, China
Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
RECRUITING

Jinan, Shandong, 250117, China

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