HIV hiding spots revealed in treatment pause study
NCT ID NCT05419024
First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 7 times
Summary
This study aims to understand where HIV hides in the body when people stop their daily antiretroviral therapy (ART) for a short time. Fifty adults with HIV will either stay on ART or pause it for up to 90 days. Researchers will use PET/CT scans and take small tissue samples from lymph nodes to measure virus levels and immune responses.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal where HIV hides in the body, pointing toward new strategies to control or eliminate the virus.
- What could go wrong
- This is a small, early-phase study focused on observation, not treatment. The treatment interruption carries risks of viral rebound and immune decline.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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