HIV patients pause meds in closely watched study

NCT ID NCT04359186

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study pauses HIV medication in 40 volunteers to closely monitor how the virus and body interact during the earliest stages of rebound. Participants stop their antiretroviral therapy and undergo frequent testing, resuming treatment within three weeks. The goal is to learn more about HIV persistence, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could reveal how HIV rebounds after stopping medication, guiding future strategies for long-term remission.
What could go wrong
This is a small, early-stage observational study with no direct treatment benefit. Participants may experience virus rebound or side effects from stopping therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94110, United States

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Other studies related to the condition(s) this trial covers.