Could early CMV and TB treatment save HIV-Positive infants with severe pneumonia?
NCT ID NCT03915366
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times
Summary
This study looked at whether giving HIV-infected babies (ages 1 month to 1 year) early treatment for two common infections—cytomegalovirus (CMV) and tuberculosis (TB)—could help them survive severe pneumonia. Over 500 infants were enrolled and followed for up to a year. The goal was to see if this approach reduces deaths and hospital stays.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cemtro de Investigaçao em Saúde da Manhiça
Manhiça, Mozambique
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Fundación para la Investigación Biomédica del Hospital 12 de Octubre
Madrid, 28041, Spain
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Hospital Central Maputo
Maputo, Mozambique
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INSERM
Toulouse, France
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Lusaka Teaching Hospital
Lusaka, Zambia
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Makerere University - Mulago Hospital
Kampala, Uganda
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Malawi Liverpool Welcome Trust. Queen Elizabeth Central Hospital College of Medicine
Blantyre, Malawi
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PENTA Foundation
Padova, Italy
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Programme PACCI. Centre Hospitalier Cocody.
Abidjan, Côte d’Ivoire
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Stichting Katholieke Universiteit Radboudumc
Nijmegen, Netherlands
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University of Lincoln
Lincoln, United Kingdom
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University of Zimbabwe Clinical Research Centre
Harare, Zimbabwe
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Université de Bourdeaux
Bourdeaux, France
Conditions
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