Could two drugs help older people with HIV walk faster and feel stronger?

NCT ID NCT07144293

Summary

This study is testing whether a combination of two drugs, dasatinib and quercetin, can improve physical function in older adults with HIV who are experiencing frailty or early signs of frailty. The trial involves 82 participants aged 50+ who have had HIV for at least 10 years and are on stable treatment. Participants will receive either the drug combination or a placebo over 12 weeks to see if it helps with walking speed, balance, and overall physical ability.

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Contacts and locations

Locations

  • Alabama CRS (Site ID: 31788)

    Birmingham, Alabama, 35222, United States

  • Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS (Site ID: 107)

    Boston, Massachusetts, 02115, United States

  • Case CRS (Site ID: 2501)

    Cleveland, Ohio, 44106, United States

  • Chapel Hill CRS (Site ID: 3201)

    Chapel Hill, North Carolina, 27599, United States

  • Cincinnati CRS (Site ID: 2401)

    Cincinnati, Ohio, 45267-0405, United States

  • Columbia Physicians & Surgeons (P&S) CRS (Site ID: 30329)

    New York, New York, 10032, United States

  • Greensboro CRS (Site ID: 3203)

    Greensboro, North Carolina, 27401, United States

  • Harbor University of California Los Angeles Center CRS (Site ID: 603)

    Torrance, California, 90502, United States

  • Houston Advancing Research Team CRS (Site ID: 31473)

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital CRS (MGH CRS) (Site ID: 101)

    Boston, Massachusetts, 02114, United States

  • New Jersey Medical School Clinical Research Center CRS (Site ID: 31786)

    Newark, New Jersey, 07103, United States

  • Northwestern University CRS (Site ID: 2701)

    Chicago, Illinois, 60611, United States

  • Ohio State University CRS (Site ID: 2301)

    Columbus, Ohio, 43210, United States

  • Penn Therapeutics CRS (Site ID: 6201)

    Philadelphia, Pennsylvania, 19104, United States

  • The Ponce de Leon Center CRS (Site ID: 5802)

    Atlanta, Georgia, 30308-2012, United States

  • UCSD Antiviral Research Center CRS (Site ID: 701)

    San Diego, California, 92103, United States

  • University of California, Los Angeles CARE Center CRS (Site ID: 601)

    Los Angeles, California, 90035-4709, United States

  • University of California, San Francisco HIV/AIDS CRS (Site ID: 801)

    San Francisco, California, 94143, United States

  • University of Colorado Hospital CRS (Site ID: 6101)

    Aurora, Colorado, 80045, United States

  • University of Pittsburgh CRS (Site ID: 1001)

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Rochester Adult HIV Therapeutic Strategies Network CRS (Site ID: 31787)

    Rochester, New York, 14642, United States

  • University of Washington Positive Research CRS (Site ID: 1401)

    Seattle, Washington, 98104-9929, United States

  • Vanderbilt Therapeutics (VT) CRS (Site ID: 3652)

    Nashville, Tennessee, 37204, United States

  • Washington University Therapeutics (WT) CRS (Site ID: 2101)

    St Louis, Missouri, 63110-1010, United States

  • Weill Cornell Chelsea CRS (Site ID: 7804)

    New York, New York, 10010, United States

  • Weill Cornell Uptown CRS (Site ID: 7803)

    New York, New York, 10065, United States

  • Whitman-Walker Institute, Inc. CRS (Site ID: 31791)

    Washington D.C., District of Columbia, 20009, United States

Conditions

Explore the condition pages connected to this study.