Simple antibody test may detect hidden HIV resurgence

NCT ID NCT07665060

Ongoing Knowledge-focused Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a rapid HIV antibody test can detect when the virus rebounds in people taking antiretroviral therapy (ART). Researchers will analyze stored blood samples from 6100 HIV-positive individuals in the US and sub-Saharan Africa. They will compare antibody levels before and after viral rebound to see if the test can accurately identify those with unsuppressed virus. The goal is to find a simpler way to monitor treatment success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple, affordable test to quickly detect when HIV virus levels rise again in people on treatment.
What could go wrong: This is a retrospective study using stored samples, not a real-world test. Results may not translate to actual clinic use, and the test may not be sensitive or specific enough.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV

Contacts and locations

Locations

NYU Langone Health

New York, New York, 10016, United States

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