Heated chemo during surgery may ease life for advanced ovarian cancer patients

NCT ID NCT03188432

Completed Symptom relief Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving heated chemotherapy directly into the abdomen during surgery can improve quality of life for people with advanced ovarian, fallopian tube, or peritoneal cancer. Fifty participants received the treatment after standard chemotherapy. Researchers measured quality of life and abdominal discomfort using questionnaires. The goal was to see if this approach helps patients feel better after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Carboplatin (heated chemotherapy)
What this could lead to: If successful, this approach could improve quality of life for people with advanced ovarian cancer by reducing side effects and better targeting remaining cancer cells after surgery.
What could go wrong: This is a small, early-phase study with only 50 participants and no comparison group, so results may not apply broadly. Heated chemotherapy also carries risks like infection or organ damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

fallopian tube cancer fallopian tube neoplasm ovarian cancer ovarian carcinoma primary peritoneal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STAGE IIIC FALLOPIAN TUBE CANCER STAGE IIIC OVARIAN CANCER STAGE IIIC PRIMARY PERITONEAL CANCER STAGE IV FALLOPIAN TUBE CANCER STAGE IV OVARIAN CANCER STAGE IV PRIMARY PERITONEAL CANCER

Contacts and locations

Locations

Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States

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