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Could 25 minutes of intense exercise outperform a 45-Minute jog for metabolic health?

NCT ID NCT02706093

Disease control Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 24, 2026 · Last updated Aug 25, 2026 · Updated 1 time

Summary

This trial investigates whether high-intensity interval training (HIIT) can improve how the body uses insulin in obese adults with glucose intolerance. Participants will be assigned to either HIIT (short bursts of intense exercise) or moderate-intensity continuous training (MICT, steady-state exercise) to compare their effects on insulin sensitivity and other metabolic measures. The study aims to find the most effective exercise 'dose' for improving metabolic health and to see if people can stick with the program long-term.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT)
What this could lead to
If HIIT proves more effective, it could offer a time-efficient exercise strategy to improve metabolic health and reduce diabetes risk in obese adults.
What could go wrong
The trial is early-stage and may not show a clear benefit of HIIT over standard exercise. Adherence to the intense regimen could be challenging, and results may not apply to all obese individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

May 2016

Finished

May 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age: 18-40 * Body Mass Index: 30-40 kg/m2 * Waist circumference: 88-98cm for women and 100-110cm for men * No regularly planned exercise/physical activity * Women must have regularly occurring menses and must be premenopausal Exclusion Criteria: * EKG abnormalities as assessed by the cardiologist on the research team * Evidence/history of cardiovascular or metabolic disease * Medications known to affect lipid or glucose metabolism * Pregnant or lactating * Tobacco or e-cigarette use

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Conditions

The condition(s) this trial relates to.

glucose intolerance obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Glucose intolerance

Contacts and locations

Locations

  • Suzette Howton

    Ann Arbor, Michigan, 48178, United States

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