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Could intense workouts be safe after a rare heart attack? a trial puts HIIT to the test

NCT ID NCT07785765

Disease control Sponsor: Oslo University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time

Summary

This trial tests whether a supervised 12-week high-intensity interval training (HIIT) program can safely improve cardiorespiratory fitness in adults who have previously had spontaneous coronary artery dissection (SCAD), a cause of heart attack that often affects younger women. Participants are randomly assigned to either the HIIT program or usual care, which advises avoiding high-intensity exercise. The study measures changes in peak oxygen uptake, monitors for major heart-related events, and tracks quality of life, anxiety, and depression.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Supervised high-intensity interval training (HIIT) on a treadmill
What this could lead to
If it works, this could show that supervised HIIT is a safe and effective way to improve heart and lung fitness in people who have had a SCAD-related heart attack.
What could go wrong
This is a relatively small, early-stage trial, and the exercise program may not improve fitness more than usual care. There is also a risk that high-intensity exercise could trigger heart-related complications, which the study monitors closely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Confirmed SCAD, at least 12 weeks since last event, age 18 years or older, medically stable and cleared for CPET and supervised exercise Exclusion Criteria: * Disease with exercise restrictions, exercise related severe hypertension on CPET (\>220 mmHg in Systolic blood pressure or \>110mmHg in Diastolic blood pressure)

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Conditions

The condition(s) this trial relates to.

idiopathic spontaneous coronary artery dissection Motor Activity myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

High intensity interval training Myocardial infarction (MI) Spontaneous coronary artery dissection

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Rikshospitalet, Department of Cardiology, ProCardio Center for Innovation

    Oslo, 0372, Norway

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