Could a hidden artery condition explain heart attacks in young women?

NCT ID NCT02799186

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study investigates whether fibromuscular dysplasia (FMD), a condition that causes abnormal growth in artery walls, is more common in people who have had a spontaneous coronary artery dissection (SCAD) — a tear in a heart artery that can cause a heart attack, often in young women without typical risk factors. Researchers will analyze blood samples for genetic markers and use imaging to check for FMD in multiple artery beds. The goal is to confirm the suspected association and uncover genetic determinants that might explain why SCAD happens.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
blood sample for genetic analysis
What this could lead to
If the link is confirmed, it could lead to better screening and earlier detection of SCAD risk in young women.
What could go wrong
This is an observational study, so it won't test a treatment. The findings may not apply to all populations, and the genetic factors may be complex.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

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