New combo therapy shows promise for tough childhood cancer
NCT ID NCT01175356
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a very strong treatment plan for children newly diagnosed with high-risk neuroblastoma, a serious nerve cell cancer. The approach combined intensive chemotherapy, a radioactive drug called 131I-MIBG, and a stem cell transplant to try to kill more cancer cells. The goal was to see if this intense regimen was feasible and safe for patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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C S Mott Children's Hospital
Ann Arbor, Michigan, 48109, United States
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Children's Healthcare of Atlanta - Arthur M Blank Hospital
Atlanta, Georgia, 30329, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Alabama
Birmingham, Alabama, 35233, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Connecticut Children's Medical Center
Hartford, Connecticut, 06106, United States
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Cook Children's Medical Center
Fort Worth, Texas, 76104, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Phoenix Childrens Hospital
Phoenix, Arizona, 85016, United States
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Primary Children's Hospital
Salt Lake City, Utah, 84113, United States
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Providence Sacred Heart Medical Center and Children's Hospital
Spokane, Washington, 99204, United States
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Seattle Children's Hospital
Seattle, Washington, 98105, United States
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UCSF Medical Center-Mission Bay
San Francisco, California, 94158, United States
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UCSF Medical Center-Parnassus
San Francisco, California, 94143, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390, United States
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University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233, United States
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
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University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Engineered immune cells take aim at childhood cancer
- Engineered immune cells take aim at childhood cancer
- New hope for tough tumors: Half-Matched bone marrow transplant trial
- New hope for kids with aggressive nerve cancer: immune-boosting combo trial opens
- Smart treatment strategy aims to spare kids with neuroblastoma from unnecessary side effects
- New study tracks hidden health costs of childhood cancer treatment