Massive study tests if a stronger flu shot keeps seniors out of the hospital

NCT ID NCT05517174

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 29 times

Summary

This large study tested whether a high-dose flu vaccine works better than the standard-dose version in adults aged 65 and older. Over 330,000 participants were randomly assigned to receive either the high-dose or standard-dose shot. The main goal was to see which vaccine better prevents hospitalizations for flu or pneumonia.

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Contacts and locations

Locations

  • Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte

    Hellerup, Capital Region, 2900, Denmark

  • Danske Lægers Vaccinations Service

    Søborg, 2860, Denmark

Conditions

Explore the condition pages connected to this study.