New High-Dose injection shows promise for major weight loss and diabetes control

NCT ID NCT05649137

Summary

This study tested a new, higher weekly dose (7.2 mg) of the injectable medication semaglutide to see if it helps people with obesity and type 2 diabetes lose more weight and better control their blood sugar than a lower dose or a placebo. Over 500 adults participated for about 1.5 years, receiving the injection along with lifestyle advice. The main goals were to measure weight loss and improvements in long-term blood sugar levels.

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Contacts and locations

Locations

  • AMC Community Endocrinology

    Albany, New York, 12203, United States

  • APDP - Associação Protectora dos Diabéticos de Portugal

    Lisbon, 1250-230, Portugal

  • ARS- Deland CRU

    DeLand, Florida, 32720, United States

  • Amarillo Med Spec LLP

    Amarillo, Texas, 79106, United States

  • Bajcsy-Zsilinszky Kórház

    Budapest, 1106, Hungary

  • Belinus Bt.

    Debrecen, Hajdú-Bihar, 4025, Hungary

  • Borbánya Praxis E.Ü. Kft.

    Nyíregyháza, Szabolcs-Szatmar Varmegye, 4405, Hungary

  • Centrum Medyczne Pratia Gdynia

    Gdynia, Pomeranian Voivodeship, 81-338, Poland

  • Chambliss Clinical Trials, LLC

    Montgomery, Alabama, 36106, United States

  • ClinDiab Egészségügyi Szolgáltató és Kereskedelmi Kft.

    Budapest, 1089, Hungary

  • DCC VII - Sofia EOOD, Endocrinology

    Sofia, 1233, Bulgaria

  • DCOL Ctr for Clin Res

    Longview, Texas, 75605, United States

  • DIABETOL, s.r.o.

    Prešov, 080 01, Slovakia

  • DIADA s.r.o.

    Bardejov, 08501, Slovakia

  • DIADA, s.r.o.

    Bardejov, 08501, Slovakia

  • Deepak Lakha

    Johannesburg, Gauteng, 1820, South Africa

  • Diab - Int, s.r.o.

    Bytča, 014 01, Slovakia

  • Diablo Clinical Research, Inc.

    Walnut Creek, California, 94598, United States

  • Dr N.K. Gounden Medical Centre

    Durban, KwaZulu-Natal, 4093, South Africa

  • Dr T Padayachee

    eMkhomazi, KwaZulu-Natal, 4170, South Africa

  • ENDOMED, s.r.o.

    Košice, 04013, Slovakia

  • Elligo Clin Res Centre

    Austin, Texas, 78704, United States

  • Fejér Megyei Szent György Oktatókórház

    Székesfehérvár, 8000, Hungary

  • Florida Inst For Clin Res LLC

    Orlando, Florida, 32825, United States

  • G.A. Research Associates Ltd.

    Moncton, New Brunswick, E1G 1A7, Canada

  • Hemant Makan

    Johannesburg, Gauteng, 1827, South Africa

  • Hope Clin Res & Wellness

    Conyers, Georgia, 30094, United States

  • Hospital da Luz Arrabida, S.A.

    Vila Nova de Gaia, 4400-346, Portugal

  • Hospital da Luz Lisboa, S.A.

    Lisbon, 1500-650, Portugal

  • IPSOMC - Dr. Georgi Marinov

    Burgas, 8000, Bulgaria

  • Jacksonville Ctr for Clin Res

    Jacksonville, Florida, 32216, United States

  • John Muir Physicians Network

    Concord, California, 94520, United States

  • Kresmed Sp. z o. o.

    Bialystok, Podlaskie Voivodeship, 15-481, Poland

  • Lausmed Kft.

    Baja, Bács-Kiskun county, 6500, Hungary

  • Lenmed Shifa Private Hospital

    Durban, KwaZulu-Natal, 4901, South Africa

  • MED-DIA CENTRUM s.r.o.

    Považská Bystrica, 01701, Slovakia

  • MED-TIMA Kft.

    Budapest, 1132, Hungary

  • MHAT - Blagoevgrad AD, Department of Internal Diseases

    Blagoevgrad, 2700, Bulgaria

  • MHAT Hadzhi Dimitar OOD

    Sliven, 8800, Bulgaria

  • MHAT Sveta Karidad EAD

    Plovdiv, 4004, Bulgaria

  • MHAT Sveti Panteleimon - Yambol AD

    Yambol, 8600, Bulgaria

  • Maxwell Centre

    Durban, KwaZulu-Natal, 4001, South Africa

  • Med. Cent. Diabet. Endo. Metabol. DIAB-ENDO-MET

    Krakow, Lesser Poland Voivodeship, 31-261, Poland

  • Medi-Clinic Bloemfontein

    Bloemfontein, Free State, 9301, South Africa

  • Medical Center Viva Feniks OOD

    Dobrich, 9300, Bulgaria

  • Milestone Research

    London, Ontario, N5W 6A2, Canada

  • NBR Polska Tomasz Klodawski

    Warsaw, 00-710, Poland

  • NZOZ "CenterMed Lublin" Sp. z o.o.

    Lublin, Lublin Voivodeship, 20-044, Poland

  • NZOZ Przychodnia Specjalistyczna Medica

    Lublin, Lubelski, 20-538, Poland

  • National Clin Res Inc.

    Richmond, Virginia, 23294, United States

  • New West Physicians PC

    Golden, Colorado, 80401, United States

  • Nova Scotia Hlth Halifax

    Halifax, Nova Scotia, B3H 1V7, Canada

  • Ocean West Research Clinic

    Surrey, British Columbia, V3Z 2N6, Canada

  • Oviedo Medical Research, LLC

    Oviedo, Florida, 32765, United States

  • PANSTWOWY INSTYTUT MEDYCZNY MSWiA

    Warsaw, 02-507, Poland

  • PharmQuest Life Sciences LLC

    Greensboro, North Carolina, 27408, United States

  • Phoenix Pharma

    Port Elizabeth, Eastern Cape, 6001, South Africa

  • PlanIt Research, PLLC

    Houston, Texas, 77079, United States

  • Precise Clinical Solutions (Pty) Ltd

    Durban, KwaZulu-Natal, 4092, South Africa

  • Premier Clinical Trial Research Network (PCTRN)

    Hamilton, Ontario, L8L 5G4, Canada

  • Selma Medical Associates

    Winchester, Virginia, 22601-3834, United States

  • Soweto Clinical Trial Centre

    Johannesburg, Gauteng, 1818, South Africa

  • Sugar Lakes Family Practice PA

    Sugar Land, Texas, 77479, United States

  • ULS De Matosinhos E.P.E.- Hospital Pedro Hispano

    Senhora Da Hora, Matosinhos, Matosinhos, 4464-513, Portugal

  • ULS De São João, E.P.E. - Hospital de São João

    Porto, 4200-319, Portugal

  • UMHAT Prof. Dr. Stoyan Kirkovich AD

    Stara Zagora, 6003, Bulgaria

  • UMHAT Pulmed OOD - Pazardzhik, Department of Internal Diseases

    Pazardzhik, 4400, Bulgaria

  • UT Southwestern Medical Center - Lingvay

    Dallas, Texas, 75390, United States

  • Unidade Local De Saúde De Lisboa Ocidental E.P.E. - Hospital Egas Moniz

    Lisbon, 1349-019, Portugal

  • Univ of Alabama Birmingham

    Birmingham, Alabama, 35222, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • Uniwersyteckie Centrum Kliniczne SUM w Katowicach

    Katowice, 40-752, Poland

  • Velocity Clin Res, Dallas

    Dallas, Texas, 75230, United States

  • Velocity Clinical Research Westlake

    Los Angeles, California, 90057, United States

  • Wharton Med Clin Trials

    Hamilton, Ontario, L8L 5G8, Canada

  • Wits Bara Clinical Trial Site

    Johannesburg, Gauteng, 2013, South Africa

Conditions

Explore the condition pages connected to this study.