Could inhaled gas help ventilator patients beat pneumonia?
NCT ID NCT06950294
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests whether high doses of inhaled nitric oxide gas are safe and potentially helpful for critically ill pneumonia patients on breathing machines. About 34 adults will receive either the gas or a sham treatment for 5 days. Researchers will monitor blood oxygen levels and recovery rates over 60 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
inhaled nitric oxide gas
What this could lead to
If it works, this could point toward a new treatment to help critically ill pneumonia patients recover faster.
What could go wrong
This is a very early, small pilot study with only 34 participants. It primarily measures safety (methemoglobin levels), not yet proven to improve outcomes. High-dose nitric oxide can cause methemoglobinemia, a blood disorder.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••