Can a gentler oxygen flow keep breathing steady during eye surgery?
NCT ID NCT04055077
First seen Aug 17, 2026 · Last updated Aug 17, 2026
Summary
This trial tests whether high-flow nasal oxygenation (HFNO) keeps breathing and oxygen levels steadier than standard low-flow nasal oxygenation (LFNO) in patients undergoing sedated vitrectomy, a type of eye surgery. Participants are normal-weight adults with different anesthesia risk levels. The study compares how well each oxygen method maintains blood oxygen and carbon dioxide levels, breathing pattern, heart rate, and blood pressure during the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- High-flow nasal oxygenation (HFNO) compared with low-flow nasal oxygenation (LFNO) during sedated eye surgery
- What this could lead to
- If HFNO proves better at maintaining stable breathing and oxygen levels during sedated eye surgery, it could become the preferred oxygen method for higher-risk patients.
- What could go wrong
- This is a single-center trial with a modest number of participants, and results may not apply to all surgical settings. HFNO may also cause discomfort or not significantly outperform standard low-flow oxygen.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University clinical hospital centre Zagreb, Croatia
Zagreb, 10000, Croatia
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