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Could skipping the breathing tube ease recovery after throat surgery?

NCT ID NCT05559502

Symptom relief Sponsor: Ajou University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 04, 2026 · Last updated Sep 04, 2026

Summary

This trial tests whether using high-flow nasal oxygen during throat surgery, instead of a breathing tube, can reduce coughing as patients wake up from anesthesia. Researchers will compare 52 adults having laryngeal microsurgery, measuring cough severity and other airway issues like sore throat. The goal is to see if this tubeless approach leads to a smoother, more comfortable recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-flow nasal oxygenation (HFNO) using a device called Optiflow, compared with endotracheal intubation using a standard breathing tube.
What this could lead to
If it works, this approach could make recovery from throat surgery smoother and more comfortable by reducing coughing and sore throat after anesthesia.
What could go wrong
This is a small, early-stage trial, so results may not apply to all patients. HFNO may not suit everyone, and there are risks like airway complications or oxygen levels dropping.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

52 people

The number who actually took part.

Started

Nov 2022

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with American Society of Anesthesiologists classification 1 or 2 who receive general anesthesia for laryngeal microsurgery Exclusion Criteria: * Patients with major cardiovascular, pulmonary, and cerebrovascular disease * Laser laryngeal surgery * Morbid obesity (BMI\>35 kg/m2)

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Conditions

The condition(s) this trial relates to.

Cough

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cough

Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, Gyeongki-do, 443-721, South Korea

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