Can a simple Oxygen-Weaning protocol keep breathing patients off the ventilator?
NCT ID NCT07638293
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a step-by-step protocol for stopping high-flow nasal oxygen therapy against usual doctor-led care in 148 adults with acute respiratory failure. The protocol uses oxygen levels and breathing rate to decide when to stop. The goal is to see if a standard approach reduces the chance of needing to restart oxygen or move to a breathing machine.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
high-flow nasal therapy weaning protocol
What this could lead to
If successful, this could establish a standard way to safely stop high-flow oxygen therapy, reducing hospital stays and preventing breathing setbacks.
What could go wrong
This is a small, early-stage trial (148 participants) testing a process, not a new drug. The protocol may not work better than doctors' judgment, and results may not apply to all patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACUTE RESPIRATORY FAILURE (ARF) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Pulmonology Unit, ASST Santi Paolo e Carlo. Department of Health Sciences, University of Milan, Milan (Italy)
RECRUITINGMilan, Lombardy, 20142, Italy
-
Pulmonology Unit, University Hospital "G. Rodolico-San Marco"
NOT_YET_RECRUITINGCatania, Sicily, 95123, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••