New drug duo takes on recurrent brain cancer

NCT ID NCT07678684

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This study tests whether an investigational drug called HF1K16, when combined with the approved drug bevacizumab, can help people with recurrent or progressive glioma—a type of brain tumor. The trial enrolls about 30 adults whose tumors have returned or worsened after prior treatment. Researchers will monitor tumor response, side effects, and how long participants live without the disease getting worse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HF1K16 combined with bevacizumab

What this could lead to

If successful, this combination could offer a new treatment option for people with recurrent or progressive glioma who have run out of standard therapies.

What could go wrong

This is an early Phase 2 study with only 30 participants, so results may not apply broadly. The combination may cause side effects or fail to slow tumor growth.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Huashan Hospital Affiliated to Fudan University

    Shanghai, Shanghai Municipality, China

    Contact

    Contact Email: •••••@•••••

    Contact