Engineered immune cells take on childhood brain cancer
NCT ID NCT04903080
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 25 times
Summary
This early-stage study tests a treatment made from a child's own immune cells, modified to recognize and attack a protein called HER2 found on ependymoma tumors. The goal is to see if it is safe and feasible for children whose tumor has returned or not responded to standard therapy. Up to 50 children will receive the cells at multiple hospitals.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30329, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90026, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Pittsburgh Children's Hospital of UPMC
Pittsburgh, Pennsylvania, 15224, United States
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Texas Children's Cancer Center
Houston, Texas, 77030, United States
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The Hospital for Sick Children
Toronto, Ontario, M5G1X8, Canada
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University of Florida
Gainesville, Florida, 32608, United States
Conditions
Explore the condition pages connected to this study.