Zambia study tracks liver health in hepatitis b and HIV patients

NCT ID NCT07589985

Recruiting now Knowledge-focused Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 390 adults in Zambia with hepatitis B, some also with HIV, to see how their liver and immune system change over time. Participants join when diagnosed or starting standard antiviral treatment and are monitored for years. The goal is to learn more about the disease, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal how the immune system controls hepatitis B, pointing toward better treatments or vaccines.
What could go wrong: This is an observational study, not a treatment trial. It will not directly test a new drug or cure, and results may take years to translate into real-world benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute hepatitis B virus infection hepatitis B virus infection HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEPATITIS B HIV

Contacts and locations

Locations

Kanyama Level 1 Hospital
RECRUITING

Lusaka, Zambia
Matero Level 1 Hospital
RECRUITING

Lusaka, Zambia
University Teaching Hospital
RECRUITING

Lusaka, Zambia

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