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Noninvasive perioperative hemodynamic monitoring in thoracic surgery: a prospective observational study

NCT ID NCT07808749

NEW Sponsor: University of Valencia Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
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Registered, but not yet taking participants.
By invitation only
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Ongoing
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The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
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Expanded access (paused)
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Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
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When the status isn't known

Details not published
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Status unknown
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First seen Sep 09, 2026 · Last updated Sep 09, 2026

Summary

Cardiorespiratory changes during lung resection surgery, even though generally well tolerated, may lead to hemodynamic compromise, reducing venous return to the heart and hence cardiac output. Carotid corrected flow time is widely regarded as non-invasive index of preload status, yet its dynamic relationship with cardiac output, especially in surgical population is not well-studied. Understanding how cardiorespiratory changes affect carotid flow time in anesthesized patients remains limited. This study investigates corrected carotid flow time response to anesthesia, lateral position, one-lung ventilation, open chest, capnothorax, lung recruitment and volume expansion, hypothesizing that cFT declines in association with CO reduction during lung resection. The secondary interest of the study is to test whether carotid flow time and its recruitment-induced change can adequately predict fluid response during one-lung ventilation. In addition, the baseline preoperative carotid flow time and its position-induced change are studied as potential predictors of hemodynamic tolerance to lung recruitment and fluid response, respectively. Finally, the purpose of this study is to see if cardiorespiratory changes and volume expansion affect cerebral blood volume during lung resection surgery.

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Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Surgical population

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients scheduled to undergo thoracosocpic lung resection surgery Exclusion Criteria: * carotid stenosis or abnormal anatomy of carotid artery that prevents visualization, emphysema, arrythmia

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemodynamic monitoring

How to take part

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  2. The official record

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Contacts and locations

Locations

  • Hospital General Valencia

    RECRUITING

    Valencia, Spain

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