Brain oxygen tracking during surgery may prevent strokes

NCT ID NCT06406842

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether monitoring the brain's oxygen levels during carotid artery surgery can help doctors manage blood pressure and reduce the risk of stroke. 560 adults scheduled for surgery will be randomly assigned to standard care or a strategy that uses a brain oxygen index to guide treatment. The goal is to see if this approach lowers the chance of new brain damage after the operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cerebral oxygenation index guided hemodynamics management (using norepinephrine or phenylephrine and adjusting oxygen or carbon dioxide levels)

What this could lead to

If successful, this approach could reduce the risk of stroke and brain injury after carotid artery surgery.

What could go wrong

This is a single-center study still recruiting, and the intervention is complex. It may not show a clear benefit or be easy to apply in other hospitals.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CEREBRAL AUTOREGULATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

carotid stenosis internal carotid artery stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tian Tan Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100070, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xuanwu Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100053, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••