Brain oxygen tracking during surgery may prevent strokes

NCT ID NCT06406842

Recruiting now Disease control Sponsor: Beijing Tiantan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether monitoring the brain's oxygen levels during carotid artery surgery can help doctors manage blood pressure and reduce the risk of stroke. 560 adults scheduled for surgery will be randomly assigned to standard care or a strategy that uses a brain oxygen index to guide treatment. The goal is to see if this approach lowers the chance of new brain damage after the operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cerebral oxygenation index guided hemodynamics management (using norepinephrine or phenylephrine and adjusting oxygen or carbon dioxide levels)
What this could lead to: If successful, this approach could reduce the risk of stroke and brain injury after carotid artery surgery.
What could go wrong: This is a single-center study still recruiting, and the intervention is complex. It may not show a clear benefit or be easy to apply in other hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

carotid stenosis internal carotid artery stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CAROTID ENDARTERECTOMY CEREBRAL AUTOREGULATION

Contacts and locations

Locations

Beijing Tian Tan Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100070, China
Xuanwu Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100053, China

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