Hormonal showdown: which treatment tames heavy periods in bleeding disorders?
NCT ID NCT05916469
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 300 teens and young adults (ages 10-24) with inherited bleeding disorders who choose either a levonorgestrel IUD or norethindrone acetate pills for heavy menstrual bleeding. Researchers will track bleeding patterns, satisfaction, and quality of life over six months to see which option works better. The goal is to provide clear guidance on managing heavy periods in this population.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Levonorgestrel intrauterine system (LNG-IUD) and norethindrone acetate (NETA)
What this could lead to
If this study succeeds, it could help doctors choose the best hormonal treatment for heavy menstrual bleeding in young people with bleeding disorders, improving their quality of life.
What could go wrong
This is an observational study, not a randomized trial, so results may be less definitive. The study is also relatively small and focused on a specific age group, so findings may not apply to everyone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Mercy
NOT_YET_RECRUITINGKansas City, Missouri, 64108, United States
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Colorado Anschutz Medical Campus
NOT_YET_RECRUITINGAurora, Colorado, 80045, United States
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Emory
NOT_YET_RECRUITINGAtlanta, Georgia, 30322, United States
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Oregon Health & Science University
RECRUITINGPortland, Oregon, 97239, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Penn State Health
NOT_YET_RECRUITINGHershey, Pennsylvania, 17003, United States
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Seattle Children's Hospital
NOT_YET_RECRUITINGSeattle, Washington, 98105, United States
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Stanford
NOT_YET_RECRUITINGPalo Alto, California, 94304, United States
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University of Michigan Medicine
NOT_YET_RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of Washington
NOT_YET_RECRUITINGSeattle, Washington, 98101, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••