BLEEDING DISORDER

This early-stage study tests a single dose of a lab-made clotting protein (recombinant von Willebrand factor) in 12 adult patients on ECMO life support who have severe bleeding. The goal is to see if the drug is safe and how the body processes it. Bleeding in ECMO patients is com…

This study looks at two hormonal treatments—a hormonal IUD and a daily pill—to see which works better for heavy menstrual bleeding in teens and young adults (ages 10-24) who also have a bleeding disorder like von Willebrand disease. Researchers will track bleeding, satisfaction, …

This study is a large registry that will follow up to 2,300 people in China with various blood diseases, such as leukemia, multiple myeloma, and hemophilia. Researchers will collect information from medical records to understand how common these diseases are, what treatments peop…

This study aims to find specific biological patterns in people who bleed easily for unknown reasons. Researchers will analyze blood samples from 400 participants to understand the different mechanisms causing the bleeding. The goal is to better classify and eventually improve car…

This study follows pregnant women with a severe hemophilia A gene and their babies after birth. The goal is to learn why some mothers have heavy bleeding after delivery and why some children develop antibodies that make hemophilia treatment less effective. By observing 500 mother…

This study is creating a huge database of health information from up to 200,000 people with blood disorders like hemophilia, sickle cell disease, and thrombosis. Researchers will use this data to better understand these conditions and improve treatments. Anyone seen at a particip…

This study follows 3,000 people with non-cancer blood disorders (like hemophilia, sickle cell disease, and clotting issues) to see how well treatments work and what side effects occur over time. Researchers will collect safety data, including allergic reactions, infections, and o…