New study aims to unlock secrets of heart transplant failure

NCT ID NCT03102125

Recruiting now Knowledge-focused Sponsor: Paul Kim Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why some transplanted hearts stop working well over time. Researchers will use heart MRI scans and advanced cell analysis to find early signs of trouble in 376 heart transplant patients. The goal is to better understand the causes of graft dysfunction so doctors can improve long-term survival for transplant recipients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Regadenoson (Lexiscan)
What this could lead to: If successful, this could help doctors detect early signs of heart transplant failure and improve how long transplanted hearts last.
What could go wrong: This is an observational study, not testing a new treatment. It may not lead to direct changes in patient care, and results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEART TRANSPLANT FAILURE AND REJECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Rejection, Psychology transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART TRANSPLANT FAILURE AND REJECTION

Contacts and locations

Locations

UC San Diego
RECRUITING

La Jolla, California, 92037, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.