New study tests if cutting insulin boosts heart health in type 1 diabetes

NCT ID NCT06609356

First seen Jan 05, 2026 · Last updated Jun 17, 2026 · Updated 19 times

Summary

This early-phase study looks at whether reducing high insulin levels (common in type 1 diabetes) with an SGLT2 inhibitor can improve heart and blood sugar health. Researchers will compare people with type 1 diabetes, those with a mild genetic diabetes (GCK-MODY), and healthy volunteers. The goal is to understand how insulin levels affect blood vessel function and insulin sensitivity.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Insulin Resistance maturity-onset diabetes of the young type 2 type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.