New study tests if cutting insulin boosts heart health in type 1 diabetes

NCT ID NCT06609356

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study looks at whether reducing high insulin levels (common in type 1 diabetes) with an SGLT2 inhibitor can improve heart and blood sugar health. Researchers will compare people with type 1 diabetes, those with a mild genetic diabetes (GCK-MODY), and healthy volunteers. The goal is to understand how insulin levels affect blood vessel function and insulin sensitivity.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

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