Lung cancer drugs may stress the heart – new study investigates

NCT ID NCT07267247

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study followed 100 people with advanced EGFR-mutant lung cancer who were taking drugs called EGFR-TKIs (erlotinib, dacomitinib, afatinib, or osimertinib). The goal was to see how often these drugs cause heart problems, specifically a drop in the heart's pumping ability. Researchers measured heart function before and during treatment to track any changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

EGFR-TKI drugs (erlotinib, dacomitinib, afatinib, osimertinib)

What this could lead to

If successful, this could help doctors better monitor and prevent heart side effects in lung cancer patients taking these drugs.

What could go wrong

This is a small, single-center observational study, so results may not apply to all patients. It only measures heart function changes, not whether these changes cause symptoms or affect survival.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cardiotoxicity non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Taichung Veterans General Hospital

    Taichung, 407, Taiwan