Genetic panel aims to spot heart risk before cancer therapy begins

NCT ID NCT07663357

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a genetic and epigenetic panel can predict heart damage caused by chemotherapy or immunotherapy in breast cancer patients. Researchers will analyze blood samples from 1,000 participants before and during treatment to see if certain genetic markers signal early risk. The goal is to catch potential heart problems sooner, allowing doctors to adjust treatment and protect patients' hearts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pharmacogenomic panel

What this could lead to

If successful, this could enable doctors to identify patients at high risk for heart damage before starting cancer treatment, allowing for safer, personalized therapy.

What could go wrong

This is an observational study, not a treatment trial. The genetic panel may not accurately predict cardiotoxicity in all patients, and results may not change outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer Cardiotoxicity neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Complexo Hospitar HUOC/PROCAPE

    NOT_YET_RECRUITING

    Recife, Pernambuco, 50100-130, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • FAMERP - Faculdade de Medicina de São José do Rio Preto

    NOT_YET_RECRUITING

    São José do Rio Preto, São Paulo, 15090-000, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital BP - A Beneficência Portuguesa de São Paulo

    RECRUITING

    São Paulo, São Paulo, 01323-900, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Beneficente UNIMAR

    NOT_YET_RECRUITING

    Marília, São Paulo, 17525-160, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto do Câncer do Ceará

    NOT_YET_RECRUITING

    Fortaleza, Ceará, 60430-230, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universidade Federal de Santa Catarina

    NOT_YET_RECRUITING

    Florianópolis, Santa Catarina, 88040-900, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••