Mayo clinic study aims to define normal vaccine reactions in kids

NCT ID NCT04112355

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study from Mayo Clinic measures how healthy children's immune systems respond to routine vaccines. Researchers will take blood samples before and after vaccination to track levels of various immune markers. The goal is to establish a range of normal responses, which could help identify when a child's immune system is not working properly. The study will also look at whether certain genetic differences affect these responses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: This study could help doctors better understand what a normal immune response to vaccines looks like in healthy children, which may improve care for kids with unusual reactions to infections.
What could go wrong: This is an observational study, not a treatment trial. It only measures responses in healthy children, so results may not apply to sick children or lead to direct medical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY CONTROLS

Contacts and locations

Locations

Mayo Clinic

Rochester, Minnesota, 55905, United States

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