Cell injection aims to repair damaged livers in early trial
NCT ID NCT07488546
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests a single injection of HCL001 cells in 39 people with decompensated cirrhosis, a severe form of liver disease. The study aims to check safety and see if the treatment can improve liver function. Participants receive one of three dose levels, and researchers will monitor them for up to 48 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HCL001 cell injection (a type of cell therapy)
What this could lead to
If successful, this could point toward a new treatment that improves liver function and reduces complications in people with advanced liver disease.
What could go wrong
This is a very early (Phase 1/2) trial with only 39 participants, so safety and effectiveness are not yet proven. Cell therapies can have unknown risks, and the results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospita
Shanghai, Shanghai Municipality, China