Pregnancy hormone may reboot brain after injury

NCT ID NCT07557615

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early study tests whether a hormone called hCG (Ovidrel) can help men recover thinking and daily living skills after a moderate to severe traumatic brain injury. Fifty men will receive either the hormone or a placebo twice a week for 24 weeks. The main goal is to check safety, but researchers will also measure changes in independence and brain function.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
human chorionic gonadotropin (hCG, Ovidrel)
What this could lead to
If it works, this could point toward a new way to boost recovery of thinking and daily function after a traumatic brain injury.
What could go wrong
This is a very early, small trial (50 men) testing safety first. It may not show clear benefit, and side effects are unknown.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • William S. Middleton Memorial Veterans Hospital, Madison, WI

    Madison, Wisconsin, 53705-2254, United States

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Other studies related to the condition(s) this trial covers.