New hope for tough cancers: first test of experimental KRAS-Targeting pill

NCT ID NCT05485974

Summary

This is the first human study of an experimental oral medication called HBI-2438 for people with advanced solid tumors that have a specific genetic change called KRAS G12C. The main goals are to find the highest safe dose and understand how the body processes the drug. The study will enroll about 44 adults with cancers like lung, colorectal, or pancreatic cancer who have tried standard treatments without success.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alliance for Multispecialty Research, LLC

    Kansas City, Missouri, 64114, United States

  • BRCR Medical Center

    Plantation, Florida, 33322, United States

  • California Cancer Associates for Research and Excellence, Inc. (cCare)

    Encinitas, California, 92024, United States

  • California Cancer Associates for Research and Excellence, Inc. (cCare)

    San Marcos, California, 92069, United States

  • Gabrail Cancer Center

    Canton, Ohio, 44718, United States

  • Innovative Clinical Research Institute (ICRI)

    Whittier, California, 90603, United States

  • Michigan Center of Medical Research

    Farmington Hills, Michigan, 48334, United States

  • Pan American Center for Oncology Trials (PanOncology Trials)

    Rio Piedras, Puerto Rico, 00935, Puerto Rico

  • Sarcoma Oncology

    Santa Monica, California, 90403, United States

  • The Oncology Institute of Hope and Innovation

    Glendale, California, 91204, United States

  • The Oncology Institute of Hope and Innovation

    Long Beach, California, 90805, United States

  • The Oncology Institute of Hope and Innovation

    Pasadena, California, 91105, United States

  • The Oncology Institute of Hope and Innovation

    Santa Ana, California, 92705, United States

  • The Oncology Institute of Hope and Innovation

    Whittier, California, 90603, United States

Conditions

Explore the condition pages connected to this study.